isolated thrombocytopenia report of a rare presentation of childhood systemic lupus erythematosus

نویسندگان

ahmad tamaddoni non-communicable pediatric diseases research center, babol university of medical sciences, babol, iran

behnaz yousefghahari department of internal medicine, babol university of medical sciences, babol, iran

afshin khani student research committee, babol university of medical sciences, babol, iran

mohammadreza esmaeilidooki non-communicable pediatric diseases research center, babol university of medical sciences, babol, iran

چکیده

background: systemic lupus erythematosus (sle) has various presentations in children. hematologic abnormalities is common in childhood onset of sle, however, isolated thrombocytopenia is relatively rare. thus, we present a child with isolated thrombocytopenia as a rare presentation of sle. case presentation: a 12-year-old boy with chief complaints of loss of appetite, weight loss, decreased platelet count (8000/µl) and lymph node enlargement was referred to our hospital. biopsy of lymph node showed reactive lymphadenopathy. investigations regarding infectious disease was negative. platelet count remained low after low dose steroidned therapy. antinuclear antibody (ana) and anti-double stranded dna antibody screening tests were positive with titer of 1/62 and 1/54, respectively. therefore, juvenile sle was considered as the final diagnosis and raising the dose of prednisolone to 2mg/kg/day was associated with increasing platelet count to 40000/µl and a week later to 96000/µl. conclusion: the findings of this study indicate that in cases with isolated thrombocytopenia refractory to conventional dose of steroids, sle should be considered. this study justifies serum ana and anti dna assessment in children with thrombocytopenia

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Isolated thrombocytopenia report of a rare presentation of childhood Systemic Lupus Erythematosus

 Background: Systemic lupus erythematosus (SLE) has various presentations in children. Hematologic abnormalities is common in childhood onset of SLE, however, isolated thrombocytopenia is relatively rare. Thus, we present a child with isolated thrombocytopenia as a rare presentation of SLE. Case presentation: A 12-year-old boy with chief complaints of loss of appetite, weight loss, decrease...

متن کامل

Isolated thrombocytopenia; A report of a rare presentation of childhood systemic lupus erythematosus (SLE)

BACKGROUND Systemic lupus erythematosus (SLE) has various presentations in children. Hematologic abnormalities is common in childhood onset of SLE, however, isolated thrombocytopenia is relatively rare. Thus, we present a child with isolated thrombocytopenia as a rare presentation of SLE. CASE PRESENTATION A 12-year-old boy with chief complaints of loss of appetite, weight loss, decreased pla...

متن کامل

Bicytopenia Secondary to Autoimmune Myelofibrosis as the First Presentation of an Undiagnosed Systemic Lupus Erythematosus: A Rare Case Report

Autoimmune myelofibrosis (AIMF) is considered as an infrequent cause of bone marrow fibrosis (BMF) and a rare complication of systemic lupus erythematosus (SLE). Due to its rarity, it is mistakenly diagnosed as primary myelofibrosis (MF). We describe the clinicopathologic features of a secondary form of AIMF in a 33- year- old female patient with an undiagnosed SLE which presented with acute b...

متن کامل

Unusual presentation of childhood Systemic Lupus Erythematosus

Bullous systemic lupus erythematosus is a rare blistering condition with a distinctive combination of clinical, histological and immunopathologic features that together constitute a unique bullous disease phenotype. It is often associated with autoimmunity to type VII collagen. Here we report a child who presented with bullous systemic lupus erythematosus. Rapid resolution of the blisters occur...

متن کامل

A Case of Systemic Lupus Erythematosus

SUMMARY During the course of systemic lupus erythematosus in a 10 year-old girl, a go it er develo ped. Subc linical I ly pothyrnic.Jism was found, in addition rising titer of ant imicrosomal antibody and overt hypothyroidism after 6-week cessation of thyroxin tablet lead to the diagnosis of Hashimoto's thyroiditis. Antibodies directed to the thyroid may result in an autoimmune thyroiditis in...

متن کامل

Hypocomplementemic urticarial vasculitis: a rare presentation of systemic lupus erythematosus.

BACKGROUND Urticarial vasculitis is a small-vessel vasculitis, presenting clinically as persistent urticarial skin lesions and microscopically as leucocytoclastic vasculitis. Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a distinct type of urticarial vasculitis with multiorgan involvement, whose etiology and link with other diseases are still unknown. Some authors have suggested t...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
caspian journal of internal medicine

جلد ۶، شماره ۳، صفحات ۱۷۴-۱۷۶

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023